Mechnikov Research Institute of Vaccines and Sera, Moscow, Russia
Monitoring of antibodies in healthy and ill persons with various diseases has been performed using ELISA systems. Features of antibacterial and anti-tissue immunity which depended from type of disease as well as significant differences from the same characteristics in healthy donors were revealed. Results of the monitoring point to fundamental importance of microorganisms in the development of non-infectious and autoimmune diseases, whereas absence of elevated levels of antibodies to 14 species of opportunistic bacteria — to the role of other bacteria and viruses in the pathogenesis of such diseases. Frequent simultaneous detection of antibodies to bacterial and tissues" antigens confirms the important role of opportunistic bacteria in the induction of autoimmune processes.
Zh. Mikrobiol. (Moscow), 2007, No. 3, P. 42—47