Ivanova, I.A., Vasilyeva, G.I., Kozlovsky, V.N., Kiseleva, A.K., Bespalova, I.A., Doroshenko, E.P.

Influence of neutrophilokines on population and subpopulation repertoire of lymphocytes and their functional activity during immune response against plague

Research Institute for Plague Control, Rostov-on-Don, Russia

Results of experimental study of regulatory effect of nutrophilokines induced by Yersinia pestis EV strain on population and subpopulation repertoire of lymphocytes and their functional activity during immune response against plague infection are presented. It was established that these neutrophilokines stimulate CD4+ and suppress CD8+ lymphocytes. Helper effect of neutrophilokines on functional activity of lymphocytes was more pronounced during secondary than during primary immune response.
Zh. Mikrobiol. (Moscow), 2009, No. 1, P. 5255